Cell Syst. 2025 Jun 18;16(6):101298. doi: 10.1016/j.cels.2025.101298.
ABSTRACT
The “objective function” is a core concept in metabolic network modeling. Its use has enabled the analysis of large data to drive deeper understanding of cellular metabolism. This commentary reframes how the objective function is discussed to enhance its value and clarify misunderstandings in metabolic network modeling.
PMID:40541323 | DOI:10.1016/j.cels.2025.101298